2000
S. typhimurium DT104 is a widespread and internationally important human and animal pathogen. Clinical manifestations of gastrointestinal infection may be more severe with DT104 although there is no evidence that it is more invasive than other Salmonella spp. Isolates of the epidemic strain of DT104 can show resistance to up to nine different antibiotics. For the proper control of DT104 and similar pathogens it will be necessary to ameliorate farm hygiene and biosecurity, improve animal husbandry and herd and flock health programmes, limit the use of antibiotics in agriculture, enhance surveillance with definitive typing of zoonotic pathogens from animals, foods and humans, and maintain strict hygiene in food processing and commercial and domestic kitchens.
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